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Sickle Cell Disease – What Causes Sickle Cell Disease

1 comment to Sickle Cell Disease – What Causes Sickle Cell Disease

  • Youness

    The video left out the cause of sickle cell anaemia which is a defective gene causing the order of aminoacids in some of the polypeptide chains to change.The new HaemoglobinS tertiary structure is changed resulting in less solubilty and it also causes it to crystalise in low oxygen concentrations. It also left out codominance of the gene and natural selection favouring heterozygous alleles due to resistance to malaria.

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